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In addition to being an essential detoxification mechanism for structurally diverse drugs, glucuronidation also leads to a short duration of action and loss of pharmacological activity

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Acetaldehyde is also responsible for the development of liver disease and is a known neurotoxin that can contribute to cognitive decline with chronic binge drinking

Longevity & Cellular Stress Models Declining GSH:GSSG ratios are a marker in cellular-senescence and oxidative-stress research, making glutathione a common reference compound in longevity studies